Louisville · the midpoint
Louisville is the most populous city in the U.S. state of Kentucky, sixth-most populous city in the Southeast, and the 27th-most-populous city in the United States. Read more →
The fair place to meet is Louisville, KY — the city closest to the midpoint of Cincinnati and Indianapolis. From the farther side that’s about 2 hr 40 min of driving.
Recommended midpoint
Louisville, KY
From Cincinnati
2 hr 14 min
89 mi to Louisville
From Indianapolis
2 hr 40 min
107 mi to Louisville
Cincinnati has the shorter trip; the split is off by about 26 min. The alternatives below can even it out. Cincinnati and Indianapolis are about 99 miles apart.
Cincinnati and Indianapolis are about 99 miles apart by road. Split the difference and you arrive near Louisville, the city closest to the halfway point between them. That puts roughly 2 hr 14 min of driving on the Cincinnati side and 2 hr 40 min on the Indianapolis side — the fairest single meeting point among the cities near the middle.
At this range, Louisville works for a same-day meetup: close enough from both Cincinnati and Indianapolis to meet for lunch or an afternoon and still be home by evening.
If Louisville doesn't have what you're after, Columbus and Chicago are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Cincinnati and Indianapolis.
Louisville is the most populous city in the U.S. state of Kentucky, sixth-most populous city in the Southeast, and the 27th-most-populous city in the United States. Read more →
Cincinnati is the most populous city in Hamilton County, Ohio, United States, and its county seat. Read more →
Indianapolis, colloquially known as Indy, is the capital and most populous city of the U.S. state of Indiana and the county seat of Marion County. Indianapolis is situated in the state's central till plain region along the west fork of the White River. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.