Louisville · the midpoint
Louisville is the most populous city in the U.S. state of Kentucky, sixth-most populous city in the Southeast, and the 27th-most-populous city in the United States. Read more →
The fair place to meet is Louisville, KY — the city closest to the midpoint of Detroit and Memphis. From the farther side that’s about 6 hr 43 min of driving.
Recommended midpoint
Louisville, KY
From Detroit
6 hr 37 min
316 mi to Louisville
From Memphis
6 hr 43 min
320 mi to Louisville
That’s an even split — both sides drive within 6 min of each other. Detroit and Memphis are about 623 miles apart.
Detroit and Memphis are about 623 miles apart by road. Split the difference and you arrive near Louisville, the city closest to the halfway point between them. That splits the trip almost evenly — about 6 hr 37 min from Detroit and 6 hr 43 min from Memphis.
That's a half-day drive from each side, so Louisville suits an overnight or a weekend rather than a quick coffee — long enough to want a reason to stay, short enough to drive.
If Louisville doesn't have what you're after, Indianapolis and Cincinnati are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Detroit and Memphis.
Louisville is the most populous city in the U.S. state of Kentucky, sixth-most populous city in the Southeast, and the 27th-most-populous city in the United States. Read more →
Detroit is the most populous city in the U.S. state of Michigan. It is situated on the bank of the Detroit River across from the Canadian city of Windsor, Ontario. It is the 26th-most populous city in the United States and the largest U.S. Read more →
Memphis is a city in Shelby County, Tennessee, United States, and its county seat. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.