San Diego · the midpoint
San Diego is a city on the Pacific coast of Southern California, adjacent to the Mexico–United States border. It is the eighth-most populous city in the U.S. Read more →
The fair place to meet is San Diego, CA — the city closest to the midpoint of Honolulu and Indianapolis. From the farther side that’s about 54 hr 42 min of driving.
Recommended midpoint
San Diego, CA
From Honolulu
54 hr 42 min
2,608 mi to San Diego
From Indianapolis
37 hr 26 min
1,785 mi to San Diego
Indianapolis has the shorter trip; the split is off by about 17 hr 16 min. The alternatives below can even it out. Honolulu and Indianapolis are about 4,338 miles apart.
Honolulu and Indianapolis are about 4,338 miles apart by road. Split the difference and you arrive near San Diego, the city closest to the halfway point between them. That puts roughly 54 hr 42 min of driving on the Honolulu side and 37 hr 26 min on the Indianapolis side — the fairest single meeting point among the cities near the middle.
Over this distance most people will fly rather than drive the whole way. San Diego still makes a fair, central place for Honolulu and Indianapolis to converge, splitting the travel instead of asking one side to cross the country.
If San Diego doesn't have what you're after, Los Angeles and San Jose are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Honolulu and Indianapolis.
San Diego is a city on the Pacific coast of Southern California, adjacent to the Mexico–United States border. It is the eighth-most populous city in the U.S. Read more →
Honolulu is the capital and most populous city of the U.S. state of Hawaii, located in the Pacific Ocean. It is the county seat of the consolidated City and County of Honolulu, situated along the southeast coast of the island of Oʻahu. Read more →
Indianapolis, colloquially known as Indy, is the capital and most populous city of the U.S. state of Indiana and the county seat of Marion County. Indianapolis is situated in the state's central till plain region along the west fork of the White River. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.