Atlanta · the midpoint
Atlanta is the capital and most populous city of the U.S. state of Georgia. It is the county seat of Fulton County and extends into neighboring DeKalb County. Read more →
The fair place to meet is Atlanta, GA — the city closest to the midpoint of Indianapolis and Tampa. From the farther side that’s about 8 hr 58 min of driving.
Recommended midpoint
Atlanta, GA
From Indianapolis
8 hr 58 min
427 mi to Atlanta
From Tampa
8 hr 44 min
417 mi to Atlanta
That’s an even split — both sides drive within 14 min of each other. Indianapolis and Tampa are about 843 miles apart.
Indianapolis and Tampa are about 843 miles apart by road. Split the difference and you arrive near Atlanta, the city closest to the halfway point between them. That splits the trip almost evenly — about 8 hr 58 min from Indianapolis and 8 hr 44 min from Tampa.
Over this distance most people will fly rather than drive the whole way. Atlanta still makes a fair, central place for Indianapolis and Tampa to converge, splitting the travel instead of asking one side to cross the country.
If Atlanta doesn't have what you're after, Birmingham and Nashville are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Indianapolis and Tampa.
Atlanta is the capital and most populous city of the U.S. state of Georgia. It is the county seat of Fulton County and extends into neighboring DeKalb County. Read more →
Indianapolis, colloquially known as Indy, is the capital and most populous city of the U.S. state of Indiana and the county seat of Marion County. Indianapolis is situated in the state's central till plain region along the west fork of the White River. Read more →
Tampa is a major city on the Gulf Coast of the U.S. state of Florida and the county seat of Hillsborough County. Tampa's borders include the north shore of Tampa Bay and the east shore of Old Tampa Bay. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.