The fair place to meet is Denver, CO — the city closest to the midpoint of Louisville and Seattle. From the farther side that’s about 21 hr 43 min of driving.
Recommended midpoint
Denver, CO
From Louisville
21 hr 43 min
1,036 mi to Denver
From Seattle
21 hr 23 min
1,020 mi to Denver
That’s an even split — both sides drive within 20 min of each other. Louisville and Seattle are about 1,939 miles apart.
Louisville and Seattle are about 1,939 miles apart by road. Split the difference and you arrive near Denver, the city closest to the halfway point between them. That splits the trip almost evenly — about 21 hr 43 min from Louisville and 21 hr 23 min from Seattle.
Over this distance most people will fly rather than drive the whole way. Denver still makes a fair, central place for Louisville and Seattle to converge, splitting the travel instead of asking one side to cross the country.
If Denver doesn't have what you're after, Salt Lake City and Omaha are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Louisville and Seattle.
Denver is the capital and most populous city of the U.S. state of Colorado. Officially a consolidated city and county, it is located in the South Platte River valley on the western edge of the High Plains, and is just east of the Front Range of the Rocky… Read more →
Louisville is the most populous city in the U.S. state of Kentucky, sixth-most populous city in the Southeast, and the 27th-most-populous city in the United States. Read more →
Seattle is the most populous city in the U.S. state of Washington and the Pacific Northwest region of North America. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.