Louisville · the midpoint
Louisville is the most populous city in the U.S. state of Kentucky, sixth-most populous city in the Southeast, and the 27th-most-populous city in the United States. Read more →
The fair place to meet is Louisville, KY — the city closest to the midpoint of Memphis and Pittsburgh. From the farther side that’s about 7 hr 11 min of driving.
Recommended midpoint
Louisville, KY
From Memphis
6 hr 43 min
320 mi to Louisville
From Pittsburgh
7 hr 11 min
343 mi to Louisville
Memphis has the shorter trip; the split is off by about 28 min. The alternatives below can even it out. Memphis and Pittsburgh are about 659 miles apart.
Memphis and Pittsburgh are about 659 miles apart by road. Split the difference and you arrive near Louisville, the city closest to the halfway point between them. That puts roughly 6 hr 43 min of driving on the Memphis side and 7 hr 11 min on the Pittsburgh side — the fairest single meeting point among the cities near the middle.
That's a half-day drive from each side, so Louisville suits an overnight or a weekend rather than a quick coffee — long enough to want a reason to stay, short enough to drive.
If Louisville doesn't have what you're after, Cincinnati and Nashville are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Memphis and Pittsburgh.
Louisville is the most populous city in the U.S. state of Kentucky, sixth-most populous city in the Southeast, and the 27th-most-populous city in the United States. Read more →
Memphis is a city in Shelby County, Tennessee, United States, and its county seat. Read more →
Pittsburgh is a city in Allegheny County, Pennsylvania, United States, and its county seat. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.