The fair place to meet is Kansas City, MO — the city closest to the midpoint of Minneapolis and Omaha. From the farther side that’s about 8 hr 38 min of driving.
Recommended midpoint
Kansas City, MO
From Minneapolis
8 hr 38 min
412 mi to Kansas City
From Omaha
3 hr 28 min
165 mi to Kansas City
Omaha has the shorter trip; the split is off by about 5 hr 10 min. The alternatives below can even it out. Minneapolis and Omaha are about 290 miles apart.
Minneapolis and Omaha are about 290 miles apart by road. Split the difference and you arrive near Kansas City, the city closest to the halfway point between them. That puts roughly 8 hr 38 min of driving on the Minneapolis side and 3 hr 28 min on the Omaha side — the fairest single meeting point among the cities near the middle.
At this range, Kansas City works for a same-day meetup: close enough from both Minneapolis and Omaha to meet for lunch or an afternoon and still be home by evening.
If Kansas City doesn't have what you're after, Milwaukee and Chicago are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Minneapolis and Omaha.
Kansas City, abbreviated KC or KCMO, is the largest city in the U.S. state of Missouri by both population and area. It is located on the Missouri River at its confluence with the Kansas River, within Jackson, Clay, Platte and Cass counties. Read more →
Minneapolis is a city in Hennepin County, Minnesota, United States, and its county seat. With a population of 429,954 as of the 2020 census, it is the state's most populous city. Read more →
Omaha is the most populous city in the U.S. state of Nebraska. It is located in the Midwestern United States along the Missouri River, about 10 mi (15 km) north of the mouth of the Platte River. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.