The fair place to meet is Oklahoma City, OK — the city closest to the midpoint of Omaha and San Antonio. From the farther side that’s about 8 hr 50 min of driving.
Recommended midpoint
Oklahoma City, OK
From Omaha
8 hr 35 min
409 mi to Oklahoma City
From San Antonio
8 hr 50 min
421 mi to Oklahoma City
That’s an even split — both sides drive within 15 min of each other. Omaha and San Antonio are about 830 miles apart.
Omaha and San Antonio are about 830 miles apart by road. Split the difference and you arrive near Oklahoma City, the city closest to the halfway point between them. That splits the trip almost evenly — about 8 hr 35 min from Omaha and 8 hr 50 min from San Antonio.
Over this distance most people will fly rather than drive the whole way. Oklahoma City still makes a fair, central place for Omaha and San Antonio to converge, splitting the travel instead of asking one side to cross the country.
If Oklahoma City doesn't have what you're after, Dallas and Kansas City are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Omaha and San Antonio.
Oklahoma City, often shortened to OKC, is the capital and most populous city in the U.S. state of Oklahoma. It is the 21st-most populous U.S. city and 8th largest in the Southern United States, with a population of 681,054 at the 2020 census. Read more →
Omaha is the most populous city in the U.S. state of Nebraska. It is located in the Midwestern United States along the Missouri River, about 10 mi (15 km) north of the mouth of the Platte River. Read more →
San Antonio is a city in the U.S. state of Texas. It is the seventh-most populous city in the United States, the second-most populous city in Texas, and the second-most populous city in the Southern U.S., with a population of 1.43 million at the 2020 census. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.