The fair place to meet is Denver, CO — the city closest to the midpoint of Orlando and Seattle. From the farther side that’s about 32 hr 29 min of driving.
Recommended midpoint
Denver, CO
From Orlando
32 hr 29 min
1,549 mi to Denver
From Seattle
21 hr 23 min
1,020 mi to Denver
Seattle has the shorter trip; the split is off by about 11 hr 6 min. The alternatives below can even it out. Orlando and Seattle are about 2,546 miles apart.
Orlando and Seattle are about 2,546 miles apart by road. Split the difference and you arrive near Denver, the city closest to the halfway point between them. That puts roughly 32 hr 29 min of driving on the Orlando side and 21 hr 23 min on the Seattle side — the fairest single meeting point among the cities near the middle.
Over this distance most people will fly rather than drive the whole way. Denver still makes a fair, central place for Orlando and Seattle to converge, splitting the travel instead of asking one side to cross the country.
If Denver doesn't have what you're after, Oklahoma City and Albuquerque are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Orlando and Seattle.
Denver is the capital and most populous city of the U.S. state of Colorado. Officially a consolidated city and county, it is located in the South Platte River valley on the western edge of the High Plains, and is just east of the Front Range of the Rocky… Read more →
Orlando is a city in and the county seat of Orange County, Florida, United States. Part of Central Florida, it is the fourth-most populous city in the state and its most populous inland city, with a population of 307,573 at the 2020 census. Read more →
Seattle is the most populous city in the U.S. state of Washington and the Pacific Northwest region of North America. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.