The fair place to meet is San Antonio, TX — the city closest to the midpoint of Los Angeles and Miami. From the farther side that’s about 25 hr 12 min of driving.
Recommended midpoint
San Antonio, TX
From Los Angeles
25 hr 12 min
1,202 mi to San Antonio
From Miami
24 hr 4 min
1,148 mi to San Antonio
Miami has the shorter trip; the split is off by about 1 hr 8 min. The alternatives below can even it out. Los Angeles and Miami are about 2,336 miles apart.
Los Angeles and Miami are about 2,336 miles apart by road. Split the difference and you arrive near San Antonio, the city closest to the halfway point between them. That puts roughly 25 hr 12 min of driving on the Los Angeles side and 24 hr 4 min on the Miami side — the fairest single meeting point among the cities near the middle.
Over this distance most people will fly rather than drive the whole way. San Antonio still makes a fair, central place for Los Angeles and Miami to converge, splitting the travel instead of asking one side to cross the country.
If San Antonio doesn't have what you're after, Austin and Houston are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Los Angeles and Miami.
San Antonio is a city in the U.S. state of Texas. It is the seventh-most populous city in the United States, the second-most populous city in Texas, and the second-most populous city in the Southern U.S., with a population of 1.43 million at the 2020 census. Read more →
Los Angeles (LA) is the most populous city in the U.S. state of California, and the commercial, financial, and cultural center of Southern California. Read more →
Miami is a coastal city in the U.S. state of Florida. It is the second-most populous city proper in Florida, with a population of 442,241 at the 2020 census. Read more →
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.
Estimates use straight-line distance and typical road speeds; real drive times vary with route and traffic.