Los Angeles and Nashville are about 1,777 miles apart by road. Split the difference and you arrive near Albuquerque, the city closest to the halfway point between them. That puts roughly 13 hr 54 min of driving on the Los Angeles side and 23 hr 25 min on the Nashville side — the fairest single meeting point among the cities near the middle.
Over this distance most people will fly rather than drive the whole way. Albuquerque still makes a fair, central place for Los Angeles and Nashville to converge, splitting the travel instead of asking one side to cross the country.
If Albuquerque doesn't have what you're after, Oklahoma City and El Paso are also close to the midpoint and worth a look — each keeps the drive reasonably balanced between Los Angeles and Nashville.
City descriptions adapted from Wikipedia (CC BY-SA); photos via Wikimedia Commons, credited above.